Investigating the protection of heart and kidneys in patients with severe kidneyfailure

Welcome to the website of the Renal Lifecycle Trial

 
With this website, we aim to inform you about the Renal Lifecycle study. This website is intended for participants, professionals, and anyone else who is interested. Here you will find general information, newsletters, updates on the progress, and the current state of affairs. By using the headings at the top, you can navigate to the various topics. You can also contact the study team via the contact page or leave messages on the feedback page.

Informative

Start Spanje and Singapore

As mentioned previously, Spain and Singapore also expressed interest in participating in the study. We are pleased to report that in both countries the first patients have now been screened or already randomized. This brings us closer to the number of participants we aim for, namely 1,750.

International patient advisory board

Because we believe it is important for patients to contribute their ideas and take part in decision-making within a study, a patient advisory board has been established. Initially, only Dutch patients participated. However, as the study is now being conducted in many more countries—and as patient priorities and logistical approaches may differ per country—our advisory board has now become international. With the addition of participants from Spain, Germany, Belgium, and Australia, we are better able to meet the diverse needs and practices. Every three months, an online meeting is held with these members and the Groningen team for discussion. The new members will introduce themselves in the upcoming newsletters.

Experiences with participating in the study

Information about experiences with participating in research is extremely important. That is why the Dutch Kidney Patients Association (NVN) has been closely involved in this study from the very beginning. To further improve the experiences of participating in the Renal Lifecycle study, the NVN, in collaboration with researchers from the Renal Lifecycle study, has developed a questionnaire to gain an even clearer understanding of participants’ experiences. With this, we hope to gather input from as many different patient perspectives as possible and ensure that the study aligns optimally with the needs of participants. Thank you very much in advance for your cooperation!

Timeline

January 2026              First participant included in Singapore
November 2025     1500 participants included worldwide
October 2025           First participant included in Spain
April 2025               First participant included in Belgium
February 2025         1250 participants screened worldwide
Participating centers worldwide
0

Numbers of participants worldwide

Below is an overview of participants so far from study start. On the bottom bar the time, on the left bar the number of participants randomized. The colors indicate the countries involved. The numbers are participants from all patient subgroups in all participating centers in that country added up.

Participant numbers across countries from study start till January 2026 - measured globally

Here is an overview of the participants by subgroup. The colors indicate which subgroup is involved. The numbers are participants of all patients in that subgroup from all participating countries added up.

Participant numbers across patient groups from study start till January 2026 - measured globally

News

On Friday, April 5, 2024, the Renal Lifecycle symposium took place in Utrecht, the Netherlands. The symposium covered the state of the

National television

The Renal Lifecycle research has made national television! In a broadcast of the program Koffietijd (on 28-10-2022) Professor Ron Gansevoort gave information

Interview

The October issue of Wisselwerking, the membership magazine of the NVN, features an interview with Drs. Heleen Nijmeijer, trial coordinator of the